COAGULATION BALANCE AND PLATELET AGGREGATION INDICATORS IN PATIENTS WITH INFECTION COVID-19
نویسندگان
چکیده
Objective. To determine changes in coagulation balance and platelet aggregation patient during the treatment of COVID-19 infection. Methods. A pilot non-randomized prospective clinical study patients admitted to intensive care unit with acute respiratory distress syndrome diagnosis (n=50) was performed. Out 50 patients, 19 died, 31 were transferred therapeutic department. The indicators carried out once 1-3 days starting from patient’s admission hospital using analyzer ACL 10000 (Instrumentation Laboratory, USA) AP 2110 (ZAO “SOLAR”, Republic Belarus). Results. In 45 (90%) COVID-19, there is a significant increase von Willebrand factor activity 350 (244.5; 480) %. There no statistically differences level among deceased surviving patients: 450.0 (338.8; 530.5) % 342.0 (188.8; 480.0) survivors. At up 250%, mortality rate 8.3%, at 250-400% - 31.3%, more than 400% 59.1%. Significantly above normal range most fibrinogen (above 68% 4.63 (3.49; 5.87) g/L) D-dimers 88% 0.73 (0,31; 1.4) μg/ml). Antithrombin III below 56% (82 (67.1; 97.2) %). degree has strong direct correlation level: an ADP inducer 0.3 μg/ml (R=0.71, р=0.003); 0.6 (R=0.74, р=0.0001); 1.25 (R=0.53, р=0.01). Conclusion. Analysis evaluation should be integral part What this paper adds For first time, have been assessed It found that 90% had increasedlevels ofvon factor(VWF) 480)%. addition activity, show reduction antithrombin levels, increasing fibrinogen, respectively. assessment components
منابع مشابه
Leukocytes Parameters, CRP, and Ferritin in Iranian Patients with COVID-19 Infection; A Cross-sectional Study
Background and Objective: Coronavirus disease known as COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is affecting over 200 countries all over the world. This study was aimed to identify simple and swiftly available laboratory biomarkers to help facilitate effectual triage to categorize suspected COVID-19 patients. Materials and Methods: Acco...
متن کاملNeutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in COVID-19 Patients and Control Group and Relationship with Disease Prognosis
Background: The present study aimed to compare the complete blood count (CBC) indices between COVID-19 patients and the control group, and assess the relationship of these indices with COVID-19 prognosis given the role of complete blood counts in the COVID-19 prognosis. Methods: COVID-19 patients (confirmed by PCR or CT-Scan) who visited Imam Hospital in Sari were selected in this case-control...
متن کاملthe past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
RETN Gene Polymorphisms as Risk Factor in Diabetic Patients with Covid-19 Infection
People with diabetes mellitus (DM) represent a population group that is at high risk of developing a poor prognosis for COVID-19. Having diabetes increases the risk of serious illness, ICU stay, and death from COVID-19. The current study included 150 participants with diabetes, 100 patients of whom had COVID-19 (46 male, 54 female), and 50 had diabetes only (28 male, 22 female), aged between 37...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Novosti hirurgii
سال: 2021
ISSN: ['2305-0047', '1993-7512']
DOI: https://doi.org/10.18484/2305-0047.2021.4.462